The polycomb group transcriptional modifier Bmi1 is often upregulated in numerous cancers and is intensely involved in normal and cancer stem cells, and importantly is as a prognostic indicator for some cancers, but its role in breast cancer remains unclear.Here, we found Bmi1 overexpression in 5-Fu (5-fluorouracil)-resistant MCF-7 cells (MCF-7/5-F
Excitotoxicity mediated by the N-methyl-D-aspartate receptor (NMDAR) is believed to be a primary mechanism of neuronal injury following stroke.Thus, many drugs and therapeutic peptides were developed to inhibit either the NMDAR at the cell surface or its downstream intracellular death-signaling cascades.Nevertheless, the majority of focal ischemia
The pyrolysis/devolatilization is a basic step of thermochemical processes and requires fundamental characterization.In this paper, the kinetic model of pyrolysis is specified as a one-step global reaction.This type of reaction is used to describe the thermal degradation of wheat Melissa straw samples by measuring rates of mass loss of solid matter
BackgroundHeadaches are common complaints in the emergency department (ED) and have raised concern about acute medication overuse.Chinese medicine is a major complementary and alternative medicine in China and effective for headaches.This study aims to summarize characteristics of headache patients at EDs and the utilization of Chinese medicine for
Foster Kennedy syndrome (FKS) is a rare neuro-ophthalmic syndrome that occurs because of an intracranial mass, most commonly a tumor.As a result of the intracranial mass, Healthy Home the patient develops optic atrophy on the same side of the lesion and papilledema on the contralateral side.In this case report, we present the case of a 25-year-old